The VA HDL Intervention Trial: clinical implications
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چکیده
منابع مشابه
The VA HDL intervention trial: clinical implications.
Clinical trials have clearly shown that low density lipoprotein (LDL)-cholesterol lowering reduces coronary heart disease morbidity and mortality in patients with established coronary heart disease and LDL-cholesterol above 3·4 mmol . l . However, about 40% of coronary heart disease patients do not have elevated levels of LDL-cholesterol and many of them have low levels of high density lipoprot...
متن کاملInsulin resistance and cardiovascular events with low HDL cholesterol: the Veterans Affairs HDL Intervention Trial (VA-HIT).
OBJECTIVE To assess the effect of insulin resistance and the benefit of the fibrate, gemfibrozil, on the incidence of major cardiovascular events in subjects with low HDL cholesterol and a broad range of triglyceride values who participated in the Veterans Affairs High Density Lipoprotein Intervention Trial (VA-HIT). RESEARCH DESIGN AND METHODS This intention-to-treat analysis, specified as a...
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BACKGROUND A low level of HDL cholesterol has been identified as a risk factor for stroke in observational studies. METHODS AND RESULTS Our objective was to determine whether treatment aimed at raising HDL cholesterol and lowering triglycerides reduces stroke in men with coronary heart disease and low levels of both HDL and LDL cholesterol. The study was a placebo-controlled, randomized trial...
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This report provides background regarding the Long Term Follow-Up of Patients in the NIDCD/VA Hearing Aid Clinical Trial study and serves as an introduction to the detailed reports that follow in this issue of Journal of the American Academy of Audiology. The authors investigated five- to seven-year benefit/satisfaction in participants from the original NIDCDNA Hearing Aid Clinical Trial. The n...
متن کاملValue of high-density lipoprotein (HDL) subpopulations in predicting recurrent cardiovascular events in the Veterans Affairs HDL Intervention Trial.
OBJECTIVE To test the hypothesis whether determination of high-density lipoprotein (HDL) subpopulations provides more power to predict recurrent cardiovascular disease (CVD) events (nonfatal myocardial infarction, coronary heart disease death, and stroke) than traditional risk factors in the Veterans Affairs HDL Intervention Trial (VA-HIT). METHODS AND RESULTS Apolipoprotein A-I (apoA-I)-cont...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2000
ISSN: 0195-668X
DOI: 10.1053/euhj.1999.2024